Foundations of Biochemistry, 5th Edition

Foundations in Biochemistry is a workbook designed to accompany an instructor’s chosen biochemistry textbook. The book is based on the process-oriented, guided-inquiry learning (POGIL) approach to teaching. The authors have successfully used a “lectureless” POGIL approach to teaching biochemistry. This workbook allows biochemistry instructors to incorporate the POGIL approach, in whole or in part, into their classrooms. Instructors who would like their students to engage the material and think about the bigger picture will find Foundations in Biochemistry to be a valuable addition to their biochemistry classroom. Read more at: https://pubs.acs.org/doi/10.1021/ed1005568

The companion website is available at: http://www.fobc5.com/

10 for $15! Custom Package: Select your 10 activities HERE.

Instructors should select the 10 activities from Foundations of Biochemistry they would like to use in their classroom at this link. Once we receive that order, we will contact the instructor with the following information:

• A free desk copy of the package
• The link (URL) you should share with your students so they can purchase and download the package (pdf format)
• Access to the Instructor Resources for Foundations of Biochemistry

Each page of the pdf is stamped with their name and e-mail address so that instructors can ensure that students are each purchasing their own copy and not violating the terms of the 10 for $15 agreement.

Thank you for your interest in our book of POGIL activities for the biochemistry classroom! Over the past decade, we have worked with hundreds of educators around the globe to support them in successful implementation of student-centered teaching practices in biochemistry. We know from personal experience that making instructional changes can be challenging and that there is no one-size-fits-all model. We hope our new system for creating custom electronic workbooks will empower you to make the changes that work in your classroom with your students. Please feel free to contact us at any point in the planning and teaching processes - you are not alone in this endeavor. We are happy to offer perspectives on selecting activities, integrating activities into your existing curriculum, revising your syllabus, trouble-shooting teaching challenges, and more.

Jenny Loertscher, PhD
Ph.D. in Environmental Toxicology (University of Wisconsin)

Dr. Loertscher is focused on research to understand and improve student learning in undergraduate chemistry and biochemistry. Her research in this area focuses on the ways in which faculty classroom practices influence students' understanding of foundational concepts and their ability to develop transferable skills like teamwork and analysis of complex problems.

Vicky Minderhout, PhD
Ph.D. in Chemistry/Biochemistry (Northwestern University)

Dr. Minderhout works with a community of biochemists, biologists, and chemists to identify concepts that are critical for learning in biochemistry. They design instructional strategies to target these concepts, measure changes in student learning and disseminate classroom strategies and assessment tools. She hopes to develop tools which can reliably and validly measure student learning.

Kate Frato, PhD
Ph.D. in Molecular Biophysics (Johns Hopkins University)

Dr. Frato is deeply interested in interdisciplinary research at the interface of biology, chemistry, and physics. Her group uses a combination of bioinorganic chemistry and biophysical methods to investigate the substrates, mechanisms, and biological roles of heme peroxidases, which may be involved in templating the silica frustule, a species-specific cell wall structure.

 

Forwards (To the Student, To the Instructor)

Section 1 Chemistry in an Aqueous Environment

Section 2 Amino Acids and the Primary Structure of Proteins

Section 3 Structure of the Protein α Helix

Section 4 Stabilizing Forces in Protein Structure

Section 5 The Thermodynamics of Protein Folding

Section 6 Tools of Biochemistry

Section 7 Problem-Solving Challenge: LWBGase

Section 8 Hemoglobin: Protein Structure and Function

Section 9 Enzyme Catalysis

Section 10 Enzyme Kinetics

Section 11 Enzyme Inhibition

Section 12 Enzyme Problems

Section 13 Protein Structure and Fuction Problem Solving

Section 14 Carbohydrates and Glycoproteins

Section 15 Lipid Structure and Function

Section 16 Membranes and Transmembrane Proteins

Section 17 The Potassium Ion Channel—Protein Structure and Function

Section 18 Transmembrane Proteins Problem

Section 19 DNA and the Central Dogma

Section 20 Higher Order Structure of Nucleic Acids

Section 21 Understanding the Rate Determining Step in a Metabolic Pathway

Section 22 Understanding Complex Chemical Systems in Living Organisms

Section 23 Understanding Metabolically Far From Equilibrium Reactions

Section 24 High Energy Compounds

Section 25 Enzymes in Glycolysis

Section 26 Regulation of Glycolysis and Gluconeogenesis

Section 27 Metabolic and Hormonal Control in Glycolysis and Gluconeogenesis

Section 28 Regulation of Glycogen Storage and Breakdown

Section 29 Anaerobic Metabolism Problem Solving

Section 30 Pentose Phosphate Pathway

Section 31 Exploring the Citric Acid Cycle

Section 32 Electron Transport and Oxidative Phosphorylation

Section 33 Metabolic Labeling

Section 34 Fatty Acid Degradation and Glucose Synthesis

Section 35 Understanding Fatty Acid Biosynthesis

Section 36 The Urea Cycle and the Effects of Protein Degradation

Section 37 Integrated Metabolism

Access Instructor Resources HERE.

The secure Instructor's Resources web site includes keys to the activities, detailed facilitation plans, additional skill exercises, rubrics and activities to support the course syllabus and active learning...everything you need to begin using the book (and then some)! We are happy to grant access to the Instructor Resources for instructors who formally adopt the use of this text in their classrooms. Purchase of a single copy of the book does NOT qualify for access; we must either receive an order from your campus bookstore or make arrangements for your students to purchase the book directly from our website.

Please request access to the Instructor Resources after you have formally adopted the book for use in your course(s).